Synthesis of Thienopyrimidines and Cyanopyridines as Biologically Active Agents

Neela J. Datta, Ranjan C. Khunt and A.R. Parikh*

Department of Chemistry, Saurashtra University, Rajkot- 360 005 (India)

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ABSTRACT:

Thienopyrimidines 3a-m and cyanopyridines 4a-m have been synthesised by the condensation of chalcones 2 with thiourea, conc. HCl and alanonitrile, ammonium acetate respectively. All the products have been evaluated for their antimicrobial activity against various strains of bacteria and fungi.

KEYWORDS:

Thienopyrimidines; cyanopyrimidines; antimicrobial activity