Synthesis and Antimicrobial Activity of 6-Methyl-8-Nitro Flavones

Jigar Desai; Vinod Amravat; M. D. Ankhiwala; H. B. Naik

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Synthesis and Antimicrobial Activity of 6-Methyl-8-Nitro Flavones

Jigar Desai, Vinod Amravat, M. D. Ankhiwala* and H. B. Naik

Department of Chemistry, Navyug Science College. Surat-395 009 India.

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ABSTRACT:

6-Methyl-8-nitro flavonet have been synthesized by the condensation of 2'hydroxy-3,'nitro-5,*methyl chalcone with dimethyl sufphoxide (DMSO) in the presence of catalytic amount of iodine .The structures of the compounds have been supported by elemented analysis and spectral data. These compounds were screened for antibacterial activity against S. aureus and E. Coli.

KEYWORDS:

Antimicrobial; Flavones; (DMSO)