Synthesis of Phenolic Schiff Bases and it’s Antimicrobial Activity

A.W. Raut; A.G. Doshi

Article | Open Access

Synthesis of Phenolic Schiff Bases and it’s Antimicrobial Activity

A.W. Raut and A.G. Doshi

Department of Chemistry, Shri. Shivaji Science College, Morshi Road, Amravati - 444 602 (India)

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ABSTRACT:

Schiff bases exhibit anticancer and antitubercular activities. Anticancer schiff bases have been synthesised by condensation of aniline with substituted benzaldehyde. In present communication we report the synthesis of substituted (∝-aryl imino) ethyl benzene. Substituted acetophenone were allowed to condense with substituted aniline in ethanol in presence of 2, 3 drops of concentrated H2SO4. These compounds were tested against the organism Salmonella typhi, Salmonella paratyphi, Proteous vulgaris,Xanthomonas spp, Fusarium solanii and Botryties cinerea.

KEYWORDS:

Phenolic; Antitubercular; H2SO4