Synthesis of Newly Synthesised Schiff Bases and their Antimicrobial Activity

M. D. Deshmukh; A. G. Doshi

Article | Open Access

Synthesis of Newly Synthesised Schiff Bases and their Antimicrobial Activity

M. D. Deshmukh¹ and A. G. Doshi²

¹Chemistry Department Rashtriya College, Chalisgaon - 424 101 India.

²Post Graduate Teaching Department of Chemistry Vidhya Bharti Mahavidyalaya, Amravati - 444 601 India.

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ABSTRACT:

2-Hydroxy-3-nitro-5-methyl acetophenone and 2-Hydorxy-3-Bromo 5-methyl acetophenone on condensation with aniline, o-nitroaniline, p-toludine and m-toludine in ethanol in presence of 2,3 drops of concentrated H2SO4 gives schiffbases. These schiff bases shows antimicrobial activity against test organism S. aureus, E. Co*, Saigella dysentriae and Salmonella typhi.

KEYWORDS:

Synthesis; Schiff Bases; Antimicrobial Activity