Interaction of DDt and Malathion on the Level of 5-Hydroxytryptamine [5-HT] in Rat Brain

S. Asif Zaidi; Shalini Anthwal; Noopur Sharma; V. S. Singh

Article | Open Access

Interaction of DDt and Malathion on the Level of 5-Hydroxytryptamine [5-HT] in Rat Brain

S. Asif Zaidi, Shalini Anthwal, Noopur Sharma and V. S. Singh

Department of Biochemistry, L.L.R.M. Medical College, Meerut India.

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ABSTRACT:

Malathion (200 mg/kg body wt.) and DDT (50 mg/kg body wt dairy for 7 days) increased the level of 5-hydroxytryptamine significantly in rat brain. Malathion (200 mg/kg) given to animals already exposed to DDT (60 mg/ kg body wt.) induced 58.33% increase in 5-HT level.

KEYWORDS:

Malathion; DDt; Brain; [5-HT];