ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Abstract

Biochemical study and gene expression of Glutathione-S-Transferase (GST)in induced asthma in Rat

Ferdous A. Jabir1,* Ahmed S. Al Ali2

DOI : http://dx.doi.org/10.13005/ojc/310337


Abstract:

This researchaims to stud the role of Glutathione-S-transferases in asthma under stress conditions. Also, evaluate the ability of Iraqi propolis to inhibit the free radicals production in asthmatic rats too.GST enzyme was partially purified from rats liver after induction asthma. The experimental Sprague-Dawly rats were divided into four groups. (G1) control group, (G2) asthma group, (G3) asthma treated with propolis and (G4) was treated with propolis first and then induce asthma. The results showed reduction GST activity in (G2) when compared with control group (G1), and increase activity of GST in (G3) when compared with (G2).

Keywords:

Biochemical study; gene expression; gene expression

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