ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Abstract

An eco-friendly and highly efficient route for N-acylation under catalyst-free conditions.

Souad Ouarna, Hacène K’tir, Salah Lakrout, Hamida Ghorab, Aïcha Amira, Zineb Aouf, Malika Berredjem and Nour-Eddine Aouf*

DOI : http://dx.doi.org/10.13005/ojc/310235


Abstract:

An eco-friendly, simple, mild, chemo selective and highly efficient procedure for the acylation of primary and secondary amine function in various structurally and electronically aliphatic and aromatic compounds affording their corresponding N-Ac derivatives is developed. Mild conditions, simplicity and easier work-up are the main advantages of this method.

Keywords:

N-Acylation; amine; eco-friendly; protecting groups

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