Abstract

Maghsoud Azimzadeh* and Davood Setamdideh

DOI : http://dx.doi.org/10.13005/ojc/310259

Selective reduction of a variety of aldehydes (1 equivalents) in the presence of ketones to their corresponding alcohols has been carried out by NaBH₄ (1.5 equivalents) & Na₂C₂O₄ (3 equivalents) in water as green solvent in high to excellent yields of the products. An oxalate-borane complex Na₂[(H₃B)₂C₂O₄] is possibly the active reductant in the reaction mixture. Also, Chemoselective, regioselectivity and exclusive 1,2-reduction enals to their corresponding allylic alcohols in high to excellent yields was achieved successfully with this reducing system.

Sodium Oxalate; NaBH4; Selective Reduction; Aldehydes

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