ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
     FacebookTwitterLinkedinMendeley

Abstract

Copper (I) iodide nanoparticles on polyaniline as a green, recoverable and reusable catalyst for multicomponent click synthesis of 1,4-disubstituted-1H-1,2,3-triazoles

Shervin Saadat1*, Simin Nazari2, Mozhgan Afshari3, Maryam Shahabi4, Mosadegh Keshavarz4*

 

DOI : http://dx.doi.org/10.13005/ojc/310248


Abstract:

A one-pot procedure for the synthesis of 1,4-disubstituted-1H-1,2,3-triazole derivatives via the three component coupling  reaction between terminal alkynes, benzyl halides/α-halo ketones and sodium azide in the presences of  CuI nanoparticles supported onto polyaniline (Nano CuI/PANI) catalyst in water has been developed. This heterogeneous catalyst showed high catalytic activity and 1,4-regioselectivity for click cyclization in water as a “green” solvent and good to excellent yields were obtained in all cases over repeated five runs.

Keywords:

Nanoparticles; Click chemistry; Heterogeneous catalyst; Benzyl halide; α-halo ketones; Triazole

[ View HTML Full Text]

Back to TOC