Abstract

D.O. Perevezentseva¹, K. V. Skirdin¹, E. V. Gorchakov ², V. I. Bimatov³

DOI : http://dx.doi.org/10.13005/ojc/310226

The electrochemical activity of the glutathione (GSH) at the graphite electrodes modified with gold nanoparticles (AuNP-GCE) is formed under the ratio of reactants and in solutions of supporting electrolytes  of 0, 1 M NaOH, 0,1 М phosphate buffer (pH 6.86), 0,1 M HCl, 0,1 M NaClO₄ is studied by the method of cyclic voltammetry. The dependence of the electrochemical activity of GSH on ratio of reagents HAuCl₄:Na₃C₆H₅O₇:NaBH₄, used to the preparation of sols, and the modification time of the GE surface with gold nanoparticles have been studied. The “inverse” cathodic peak of GSH at AuNP-GCE formed in the reaction mixture HAuCl₄:Na₃C₆H₅O₇:NaBH₄=1:1:4 is observed on the cathodic branch of cyclic voltammogram at E_c = 0.05 V in 0.1 M NaOH. The mechanism of electrochemical oxidation of the GSH on the surface of AuNP-GCE  in 0.1 M NaOH is proposed.

graphite electrode; gold nanoparticles; cyclic voltammetry; glutathione

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