Abstract

Rakesh P. Chaudhari^1,2, Ganesh R. Chaudhari¹ and Hemant A. Mahajan^2*

DOI : http://dx.doi.org/10.13005/ojc/400138

A novel and eco-friendly synthetic protocol has been established to prepare bisindolyl methanes using an easily recyclable ionic liquid and a minimal amount of sulfuric acid. This synthetic approach involves coupling two indole molecules with aromatic aldehydes under mild conditions. The developed synthetic route has remarkable benefits like high percentage yields, shorter time of reaction, and straightforward product isolation. Additionally, the employed ionic liquid was effectively recycled which indicates the sustainability of the synthetic approach.

Bis(indolyl) Methanes; Ionic Liquid (ILs); HEMImBr (1-(hydroxymethyl)-3-methyl-1H-imidazol-3-ium bromide)

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