ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Abstract

Synthesis and Biofunctional Evaluation of Novel Isoxazole, C-Nucleoside, and Thioxopyrimidine Derivatives

Rajendra K. Wanare1, Rajendra R. Tayade2*, Abhilash A. Sukhadeve3 , Prafulla P. Choudhari4, R. G. Mahakale5, Nihal Mishra2

DOI : http://dx.doi.org/10.13005/ojc/390526


Abstract:

Thioxopyrimidines are an important class of compounds in the fields of biology and chemistry that play significant roles in drug discovery, nucleic acid chemistry, enzyme inhibition, and various other fields of science and technology. Their structural diversity and potential bioactivities make them valuable tools for researchers. This work presents a thorough synthesis and analysis and bio-functional assessment of a variety of isoxazole C-Nucleoside, and thioxopyrimidine derivative. The structural characterization of the synthesized compounds was achieved through spectral analyses, including IR, 1H NMR, and mass spectra and also deals with its antibacterial and antifungal activity.

Keywords:

Antimicrobial activities; Benzisoxazoles; Glucosides; Pharmaceutical properties; Thiopyrimidines

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