ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Abstract

Antimicrobial Activity of Calix[4]Pyrrole-entrenched Silver Nanoparticles and its Application as Colorimetric and Spectrophotometric Sensing of L-Histidine

Nandan C. Pomal1, Keyur D. Bhatt1*, Dinesh S. Kundariya2

DOI : http://dx.doi.org/10.13005/ojc/390104


Abstract:

A calix[4]pyrrole tetrahydrazide functionalized silver nanoparticles (CPTPH-AgNPs) coupled with colorimetric findings were prepared. In the variety of essential amino acids, it detected the L-Histidine exclusively with an LOD of 6.1 μM and LOQ of 18.5 μM. The CPTPH-AgNPs were exhibited the SPR spectrum at 408 nm, which further characterized with TEM, EDEX and SAED in that they show the monodispersed spherical morphology of AgNPs with 13 ± 2 nm size. The antimicrobial potential of CPTPH-AgNPs towards Gram positive bacterial - Staphylococcus aureus, Bacillus subtilis, Gram negative bacteria - Escherichia coli, Pseudomonas aeruginosa and fungi - Aspergillus niger was evaluated.; in which it is found to give reasonable response comparable to standard antibiotic drugs.

Keywords:

Calix[4]pyrrole; Metal Nanoparticles; Silver Nanoparticles; Supramolecular Chemistry

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