Abstract

Manohar Solanki^1*, Mangla Dave Gautam² and Vijay R. Chourey³

DOI : http://dx.doi.org/10.13005/ojc/380522

Newly Zn(II)-salicylidene–4–(p-chlorophenyl)–2–aminothiazole (SCAT) ligand was synthesized and studied in DMF media by the polarographic method and produce a DC and DPP polarogram in KCl (supporting electrolyte) with Britton- Robinson buffer. The far FT- IR spectral study show signals at 465 and 412 cm−1 respectively which confirm the metal-ligand bonding. The serial tube dilution method (MIC) was used for investigating the antibacterial activity of this newly synthesized complex and ligand toward pathogenic bacteria, B. subtilis, and E. coli. The results concluded that the ligand enhanced the biological activity when it binds with Zn(II) ion.

Antibacterial activity; DCP; DPP; MIC; SCAT ligand; Zn(II) complex

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