Abstract

Santosh Laxman Kumbhare^1* and Yuvraj Khushal Meshram²

DOI : http://dx.doi.org/10.13005/ojc/380530

Nitrogen heterocyclic compounds such as2-pyrazoline showing various pharmacological activities such as antibacterial, antifungal, antioxidant, antidepressant, anti-inflammatory, anticancer, and antitubercular activities. This promotes to synthesize 2-pyrazolines by the reaction of different substituted chalcones of 2-Acetyl Furan and hydrazinehydrate in the presence alcohol. Synthesized compound was confirmed by physical data such as melting point and various spectral analysis such as FTIR, NMR spectra. Antimicrobial activity of synthesized compound was evaluated. The results indicated that some of compounds show good antibacterial and antifungal activity.

Antimicrobial activity; Antifungal activity; 2- Acetyl Furan; Chalcones; Pyrazolines; Physical data

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