Abstract

H. N. Akolkar and B. K. Karale*

DOI : http://dx.doi.org/10.13005/ojc/310151

3-Formylchromone 1 was treated with 1-(4-(4-bromophenyl)thiazol-2-yl)hydrazine 2 to get (1-(4-(4-bromophenyl)thiazol-2-yl)-1H-pyrazol-4-yl)(2-hydroxyphenyl)methanone ­­­­­­­­(3a-e). Compound 3 on treatment with NH₂OH/HCl gavethe compound 2-[(E)-{1-[4-(4-bromophenyl)-1,3-thiazol-2-yl]-1H-pyrazol-4-yl}(hydroxyimino)methyl]phenol (4a-e). Compound 4 on treatment with POCl₃ gave 2-(1-(4-(4-bromophenyl)thiazol-2-yl)-1H-pyrazol-4-yl)benzo[d]oxazole (5a-e). The synthesized compounds have been characterized with the help of spectral techniques.

Benzo[d]oxazole; Thiazole; Pyrazole; 3-Formylchromone

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