ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Abstract

Synthesis and Screening of Biologically Active Schiff bases of Benzothiazoles and its Zinc and Lanthanum Metal Complexes

D. G.Anuse1*, V. J. Desale1, B. R. Thorat1, D. D. Anuse2, S. G. Jagadhani2, K. George Abraham3 and R. S.Yamagar4

DOI : http://dx.doi.org/10.13005/ojc/370126


Abstract:

The substituted 2-Aminobenzothiazole and ethyl 2-(4-formyl-3-hydroxyphenyl)-4-methylthiazole-5-carboxylate in methanol mix together and heat the reaction mixture for overnight, It gives Schiff’s bases (derivatives of substituted aminobenzothiazole) 3. This compound 3 when treated with Zinc Chloride it gives Zinc metal complex of Schiff’s bases 4 and if compound 3 was treated with Lanthanum chloride gives Lanthanum metal complex of Schiff’s bases 5, which shows marked biological activities.

Keywords:

2-Aminobenzothiazole; Lanthanum chloride; Metal complex; Zinc chloride

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