Abstract

Laxmi Kunwar Chauhan, Kshipra Nimodia, Pradhyuman Singh Ranawat, Ajay Kumar Goswami and Prabhat Kumar Baroliya*

DOI : http://dx.doi.org/10.13005/ojc/360509

In this investigation, we report synthesis, spectrophotometric application and antimicrobial activities of 3-hydroxy-3-(4-chlorophenyl)-1-(4- sulphonamido)phenyltriazene(HCNT) and its Fe(III) complex (Fe-HCNT). The Fe-HCNT complex have been synthesized by traditional as well as mechanochemical routes. These compounds have been characterized and screened for antimicrobial activity against bacterial strains i.e. E. coli,S. aureus, S. pyogenes, P. aeruginosa and fungal strains i.e. A.clavatus, A. niger, C. albicans using brothmicrodilution method. The results indicate that the compounds may be serve as better bactericides compared to fungicides and the molar composition of iron(III) complex was found 1:2 (Fe:HCNT) by spectrophotometric study.

Antimicrobial Activity; Iron Complex; Mechanochemical Synthesis; Sulphanilamide

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