Abstract

Gopal Lal Kumawat, Preeti Choudhary, Anil Kumar Varshney and Sarita Varshney*

DOI : http://dx.doi.org/10.13005/ojc/350327

The cyclic voltammetric behavior of newly synthesized biologically active azomethine 2’-hydroxyacetophenone sulfamethoxazole (2’-HyAcPhSM) was examined at glassy carbon electrode in acetonitrile, acetone, methanol and DMF solvents using phosphate buffer and Britton-Robinson (BR) buffer. The effect of solvents, buffers, sweep rates and pH were calculated on peak potential and peak current. The cyclic voltammograms of 2’-HyAcPhSM exhibited two electronic, irreversible and diffusion-controlled single cathodic peak within the entire pH range which is attributed to the reduction of the azomethine group   (‒CH=N‒) to amine group (‒CH₂‒NH‒). The biological activity of synthesized 2’-HyAcPhSM compound were carried out against various bacteria and fungi.

Biological Activity; Cyclic Voltammetry; 2’-Hydroxyacetophenone Sulfamethoxazole

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