ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Abstract

1, 4 Dithiane 2, 5 Diol : An Versatile Monomer to Synthesis Aliphatic Random Copolyester with Biomedical Application

Kalpana Balachandran*1, Nanthini Raveendiran1 and Margaret Marie John2

DOI : http://dx.doi.org/10.13005/ojc/350253


Abstract:

This article uses 1, 4-dithiane-2, 5-diol as a monomer to synthesize aliphatic random copolyester (PDDD).PDDD was synthesized by direct melt polycondensation method and characterized by FT-IR and 1H- NMR. The physical properties of PDDD were characterized by X-ray diffraction, differential scanning calorimetry, as well as viscosity and solubility measurements. The anticancer, antioxidant, and antimicrobial activity of PDDD were evaluated to investigate its potential biomedical applications. Generally, good results were obtained. It is evident that the copolyester exhibits favorable and tunable physical, thermal and biological properties and so is a suitable candidate for biomedical applications.

Keywords:

Anticancer; Antimicrobial; Antioxidant; Copolyester; 1,4 Dithiane 2,5 Diol

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