Abstract

Riyadh J. Nahi and Noor H. Imran

DOI : http://dx.doi.org/10.13005/ojc/350128

In the current study, a new series of 1,2,3-triazole derivatives was synthesized via copper (I) catalyzed azide-alkyne cycloaddition reaction using a series of synthesised p-substituted phenyl azides and propiolic acid. In addition, a new series of heterocyclic compounds containing 1,2,3-triazole and 1,3,4-thiadiazole ring combined in one molecule was synthesised via a condensation reaction of the synthesised 1,2,3-triazole derivatives and thiosemicarbazide in the presence of POCl₃. Furthermore, the thermal behavior of these newly synthesised compounds was studied by TGA and DTG  techniques.

Click Reaction; CuAAC; Thermal Stability; 1,2,3-Triazole; 1,3,4-Thiadiazole

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