Abstract

Surya Hadi*¹, Baiq Desy Ratnasari¹, Maulida Septiyana¹, Seto Priyambodo² and I. Made Sudarma¹

DOI : http://dx.doi.org/10.13005/ojc/350133

Overall aims of this research was to study the antibacterial activity of Voacanga foetida and then studied the distribution of the alkaloidal lombine produced in the plant, in which the samples were collected from three different regions. The antibacterial activities were assayed using agar well diffusion method. The distribution of the alkaloids in Voacanga foetida, especially lombine was studied on the basis of GC-MS in several temperature programs. The result showed that the leaves and the barks of Voacanga foetida were possessing antibacterial properties. The second result, GC-MS showed that alkaloidal lombine was produced stably in the barks while not in the leaves. The abundance of lombine in the base fraction of the barks was 6.06% (West Lombok), 74.91% (East Lombok), and 2.77% (North Lombok). The outcome will be then used as a platform for further studies investigating total uses of the plant especially in finding new materials for medicine.

Antibacterial Activity; Alkaloids; GC-MS; Lombine; Voacanga Foetida

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