ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Abstract

Viscosity and Density Studies of Drugs in Aqueous Solution and in Aqueous Threonine Solution at 298.15 K

Hanaa G. Attiya, Zainab A. H. Al-Dulaimy, Kawther Ahmed Sadiq and Maida Hameed Saleem

DOI : http://dx.doi.org/10.13005/ojc/350141


Abstract:

Viscosities (η) and densities (ρ) of atenolol and propranolol hydrochloride in water and in concentrations (0.05 M) and (0.1 M) aqueous solution of threonine have been used to reform different important thermodynamic parameters like apparent molal volumes ϕv, partial molal volumes at infinite dilution ϕ, transfer volume ϕ(tr), the slop Sv, Gibbs free energy of activation for viscous flow of solution ΔG*1,2 and the B-coefficient have been calculated using Jones-Dole equation. These thermodynamic parameters have been predicted in terms of solute-solute and solute-solvent interaction.

Keywords:

Atenolol; Density; L-Threonine; Propranolol Hydrochloride; Viscosity

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