Abstract

Dwi Hudiyanti¹, Marliana Jayanti², Muhammad Fuad Al-Khafiz³ and Khairul Anam¹

DOI : http://dx.doi.org/10.13005/ojc/340636

Coconut (Cocos nucifera L.) phosphatidylcholines, or CocoPCs species are studied in this paper. CocoPCs is fractionated from coconut phospholipids (CocoPLs) using methanol eluent in silica column chromatography. Analysis of the CocoPCs, by FTIR, GCMS and LCMS, reveals that among the isolated CocoPCs species are 16:0/18:0-PC with m/z 763 at R_f 6.02 and 18:1-LysoPC with m/z 522 at R_f 4.93. The composition of CocoPCs fatty acid chain residues are Dodecanoic acid (C12:0), Tetradecanoic acid (C14:0), 9-Hexadecenoic acid (C16:1), Hexadecanoic acid (C16:0), 9,12-Octadecadienoic acid (Z,Z) (C18:2), 9-Octadecenoic acid (C18:1) and Octadecanoic acid (C18:0). The CocoPCs content is 6.317% of 100 mg CocoPLs.

Amphiphilic; Drug Delivery Systems; Fatty Acid; Natural Membrane; Phospholipid

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