Abstract

Ahmed K. Hussien, Enaam I. Yousif, Hasan A. Hasan and Riyadh M. Ahmed

DOI : http://dx.doi.org/10.13005/ojc/340340

The study includes preparation and characterisation of mixed azo-linked Schiff-base and DTCs ligands and their complexes. The starting material was isolated from the mixing of naphthyl amine diazonium salt with 2-amino phenole in a 1:1 mole ratio in water. In this work, the formation of azo-linked Schiff-base and DTCs ligands are reported. Ligand of the azo-linked Schiff-base was achieved by the reaction of starting material with 4-(dimethylamino)benzaldehyde) (HL¹)_. The DTCs was isolated by the reaction of (C₆H₅)₂NH with carbon disulphide in potassium hydroxide (L²). The complexes were prepared by mixing the azo-linked Schiff-base ligand and DTC ligand with the metal salts; Co^II, Ni^II, Zn^IIand Cd^II in a 1:1:1 mole ratio. Ligands and complexes were characterised by analytical and spectroscopic analyses including; microanalysis, chloride content, thermal analysis, magnetic susceptibility for complexes, conductance, FTIR, UV-Vis and ¹H-NMR spectroscopy. Physico-chemical techniques indicated complexes demonstrated four and six coordinate structures in the solid and solution sate. Biological activity of the ligands and their metal complexes were screened for their antimicrobial activity against four bacterial species (Escherichia coli and  Enterobacter (G-)), (Bacillus stubtilis and  Staphylococcus aureus (G+)).

Biological Activity; Dithiocarbamates (DTCs); Metal complexes; Mixed ligands; Thermal Analysis

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