ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Abstract

Synthesis and Antimicrobial Activity of Some new Pyrimidines of 6-Chlorobenzimidazoles

Indira M. Madawali, Navanath V. Kalyane, Gaviraj E. N and Shivakumar B

DOI : http://dx.doi.org/10.13005/ojc/340358


Abstract:

A new series of pyrimidines of 6-chlorobenzimidazoles have been synthesized by the reaction of chalcone derivatives of 6-chlorobenzimidazole with guanidine nitrate in ethanol and aqueous solution of sodium hydroxide for evaluating them as potent antimicrobial agents. Results reveal that, compounds exhibited significant antibacterial and antifungal activities.

Keywords:

Antimicrobial Activity; Benzimidazoles; Chalcones; Pyrimidines

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