Abstract

B.K. Rai^1*, Puja Sinha², Vineeta Singh³, S.N. Vidhyarthi⁴, Amit⁴, Ashok Pandey⁵, and Shashi Bhusan shahi⁴.

DOI : http://dx.doi.org/10.13005/ojc/300366

The complexes of Co(II), Ni(II) and Cu(II) with Schiff base 2-butyl thioquinazoline 4(3H) thiosemicarbazone were synthesized. The general formulae of the complexes are of the type {M(L)₂X₂], L=2 – butyl thioquinazoline 4(3H) thiosemicarbazone; x = Cl^-, Br^-, I^- and NO₃^-. Elemental analyses and spectral (IR, electronic) studies of the synthesized complexes suggest the presence of octahedral, environment around the central metal ion. These complexes were also subjected to study their antimicrobial screening against, Gram positive bacteria Candida albicans and gram negative bacteria Escherichia coli by disc diffusion technique.

Schiff bases;BTQT ; Complex / Co(II); Ni(II) and Cu(II); antimicrobial screening

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