Abstract

Radhiyah A. Khdur¹and Ezzat H. Zimam²

DOI : http://dx.doi.org/10.13005/ojc/340140

In this work new Azo compound was synthesized through a diazo-coupling reaction (S₁) (4-amino-N-(pyrimidine-2-yl)-3-( pyrimidine-2-yldiazenyl)benzene sulfonamide). The diazotization process of 2-aminopyrimidin with Sulphadiazine as coupling component was described, then schiff bases [B₁-B₅] prepared from condensation of the free amino group in the azo compound with many aromatic aldehydes by using glacial Acetic acid as solvent. cyclization of Shiff bases with Chloro acetyl chloride in the presence of tri ethyl amine give the corresponding β-lactam derivatives [L₁-L₅]. All these compounds identified by( FT-IR,¹H-NMR, ¹³C-NMR) and follow reaction by (TLC) and Measurement melting points of some them.

2-Amino Pyrimidine; Sulphadiazine; Schiff Base; Β-Lactam

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