Abstract

Sogand Tohidi  and Abdolhossein Rustaiyan

DOI : http://dx.doi.org/10.13005/ojc/340157

In this work we have exhibited vitamin C permeability and water transition through channel of Aquaporin. This study describes the investigation of the vitamin channel membrane proteins for selective transition among the B group vitamins and water. The interaction among the channels with some vitamins and water has been calculated. Total energy (E_tot), Potential (E_pot) and Kinetic (E_kin) energies (kcal/mol), calculated by the molecular simulation with different force fields in different temperatures. The NMR parameters have been calculated for confirming of the results.

Monte Carlo; NMR; Vitamin C; Channel Membrane; Aquaporin

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