Abstract
Linseed (Linum usitatissimum L.) as a biocatalyst for reduction of nitroaromatic compounds
Leonardo C. Tavares1, Telma Leda G. De Lemos1, Ângela Martha C. Arriaga1*, Maria Valdeline S. Teixeira1, Gilvandete Maria P. Santiago1,2 And Daniele A. Ferreira1
DOI : http://dx.doi.org/10.13005/ojc/300211
Abstract:
The reduction of nitroaromatic compounds is an important transformation that be used in the synthesis of amines which are interesting intermediates of pharmaceuticals and other derivatives. Linseed, Linum usitatissimum L., were used to catalyze biotransformations of nitrobenzene, ortho-nitroacetophenone, meta- nitroacetophenone and para-nitroacetophenone. Ortho-aminoacetophenone, and para- aminoacetophenone were obtained with excellent chemoselectivity (92.1 to ≥99%).
Keywords:Linum usitatissimum L; Linseed; Bioreduction; Nitroaromatic Compounds; Chemoselectivity.
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