Abstract

B. K. Rai^* and Arun Kumar¹

DOI : http://dx.doi.org/10.13005/ojc/290349

A series of metal complexes derivatives of 1-propyl-2-6-diphenyl piperidone semicarbazone(PDPS) with metal ions Cu(II), Co(II) and Ni(II) have been synthesized. The ligand and metal complexes obtained are characterized quantitatively and qualitatively by using, molar mass, elemental analyses, Infrared spectra, electronic spectra, magnetic susceptibility and conductivity measurements. On the basis of above physiochemical analysis, it has been observed that the ligand PDPS coordinate to the metal ion in a bidentate manner through azomethine nitrogen and oxygen atom of semicarbozone moiety. The remaining coordination centers are satisfied by anions such as X = Cl^-,  Br^- and I^-. Electronic spectral and magnetic susceptibility measurement proposed the general composition of the complex is [M(PDPS)₂X₂] where M = Cu(II), X = Cl^- and  Br^-; M = Co(II) and Ni(II), X = Cl^-,  Br^- and I^-. The complexes of Co(II) and Ni(II) were proposed octahedral geometries whereas distorted octahedral geometry reported for Cu(II) complexes. The preliminary in vitro antibacterial Screening activity revealed that complexes showed better inhibition against tested bacterial strains and higher compared to parent ligand.

PDPS;Semicarbazone;Cu(II);Co(II) and Ni(II)/complexes;antibacterial activity

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