Abstract
Synthesis of flavanones using methane sulphonic acid as a green catalyst and comparision under different conditions
R. B. Kshatriya, G. M. Nazeruddin
DOI : http://dx.doi.org/10.13005/ojc/300264
Abstract:
Flavonoids are an important class of natural products with wide range activities.Flavonoids includes flavone,flavanone,flavane & flavanol.The synthetic route invovles synthesis of chalcone followed by ring closing to give flavanone.So many catalysts were mentioned in past literature.But most efficient catalyst is methane sulphonic acid.It is easy to handle,less reaction time &easily available.Flavanones were synthesized from chalcone using methane sulphonic acid under thermal condition,microw wave and ultrasound condition.Flavanones are syntheisized in very less time compared to other conditions.
Keywords:Flavanone; methanesulphonic acid; thermal; micro wave; ultrasound.
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