ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Abstract

The Physico-Chemical and Solvolytic Study of Alprazolam Drug In Ethanol at 303 K

Chandra Kant Bhardwaj1*, Anjna Kumari2, Anjul Singh2

DOI : http://dx.doi.org/10.13005/ojc/300261


Abstract:

The physico-chemical and solute –solvent interaction of Alprazolam in ethanol were reported  at 303 K.  The solute solvent  interaction have been carriedout by computing various acoustic  parameters, Specific acoustic impedance(z),Intermolecular freelength(Lf),Isentropic compressibility (bs) , Apparent molal adiabatic compressibility  (fk  ) , Shear’s  relaxation ( ts ), and Solvation number (Sn).These parameters have been evaluated by using ultrasound velocity, density and viscosity data.These results are interpreted in terms of solute-solvent interaction between the molecules.

Keywords:

Solute-solvent interaction; Ultrasound velocity; Alprazolam.

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