Abstract
Nano Tio2: An Efficient Catalyst for The synthesis of Biscoumarins in Aqueous Medium
Hamide Babaei* and Naser Montazeri
DOI : http://dx.doi.org/10.13005/ojc/300223
Abstract:
An easy method for the synthesis of biscoumarins through a one-pot reaction of 4-hydroxycoumarin and aryl aldehydes under very mild reaction conditions using nano TiO2 as catalyst in aqueous medium is described. The products were obtained in short reaction times with excellent yields under reflux. This method is of great value because of its environmentally benign character, high yield processing, and easy handling. We believe this applicability of nano-TiO2 with mentioned advantages makes our method superior over all previous reported methods to the synthesis of biscoumarins.
Keywords:Biscoumarins; aqueous medium; 4-hydroxycoumarin; nano-TiO2; aryl aldehydes
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