Abstract

S. A. Al-Issa

DOI : http://dx.doi.org/10.13005/ojc/300209

 The highly accelerated   synthesis of thienopyrimidinones, theino- pyrimidines,thioxotheinopyrimidinones and a thienotriazolopyrimidinone derivatives under microwave irradiation is reported. Compared to conventional conditions, microwaves method offered several advantage likes short time, good yields, simple procedure, mild conditions and easy workup. The structure of synthesized compounds have been characterized on the basis of their elemental analysis and spectral data, and screened for their antimicrobial activity.

Thienopyrimidine; Thioxothienopyrimidine; Triazolopyrimidinone; Microwave Irradiation

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