Abstract
Synthesis of Precursor Imidazolium Salts for the Synthesis of N-Heterocyclic Carbines Used as Ligands for the Enantioselective Preparation of Heterosteroids Compounds
Messaoud Guerria1,2, Lakhdar Sekhri2*, Chuzel Olivier2 and Parrain Jean-Luc2
DOI : http://dx.doi.org/10.13005/ojc/300204
Abstract:
The imidazolium salts 1-phenyl-3-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propyl)-1H-imidazol-3-ium bromide (4), and 1-(pyrimidin-2-yl)-3-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propyl)-1H-imidazol-3-ium bromide (5) were respectively prepared by coupling reaction of the precursors 1-phenyl-1H-imidazole (1) and 2-(1H-imidazol-1-yl)pyrimidine (2) with 2-(3-Bromopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (3) . The purity of these compounds was confirmed by spectroscopic data. The NMR spectra showed all the signals and the structures were confirmed by HRMS.
Keywords:Imidazolium salts; ligand; NHC-Carnines; Heterosteroids
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