Abstract
A Novel Synthesis of Oxazolidinone Derivatives (A Key Intermediate of Linezolid)
Pingili Krishna Reddy1,2, K. Mukkanti2 and Dodda Mohan Rao1*
DOI : http://dx.doi.org/10.13005/ojc/290322
Abstract:
Oxazolidinone derivatives a very key intermediate of Linezolid 7(a-e) have been synthesized from 3-fluoro-4-morpholinyl aniline 2 in good yield.The structures of all the compounds were confirmed by IR, 1H NMR,C13 NMR and Mass Spectral data.
Keywords:Oxazolidinone;epichlorohydrin;Antibacterial;Linezolid
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