ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Abstract

A Novel Synthesis of Oxazolidinone Derivatives (A Key Intermediate of Linezolid)

Pingili Krishna Reddy1,2, K. Mukkanti2 and Dodda Mohan Rao1*

DOI : http://dx.doi.org/10.13005/ojc/290322


Abstract:

Oxazolidinone derivatives a very key intermediate of Linezolid 7(a-e) have been synthesized from 3-fluoro-4-morpholinyl aniline 2 in good yield.The structures of all the compounds were confirmed by IR, 1H NMR,C13 NMR and Mass Spectral data.

Keywords:

Oxazolidinone;epichlorohydrin;Antibacterial;Linezolid

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