Abstract

Aayesha Nasreen*,  Rita M. Borik

DOI : http://dx.doi.org/10.13005/ojc/300249

Cobalt(II) chloride (10mol%) was found to be an efficient catalyst for one pot synthesis  of  variety of  2-substituted-4(3H)quinazolinones by condensation of anthranilamide and aldehydes and synthesis of 3-substituted-4(3H)quinazolinones by condensation of anthranilic acid, orthoester, primary amines at reflux giving good to excellent yields (75-95%).

cobalt(II) chloride; 2-substituted and 3-substituted 4(3H)quinazolinones; anthranilamide; aldehydes, anthranilic acid; HC(OEt)3; anilines.

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