Abstract
Synthesis of a New Cyclen-based Compound as a Potent Anti-tumor Medicine
Davood Habibi1* Hiva Nabavi2, Somayyeh Heydari2, Somayyeh Vakili2
DOI : http://dx.doi.org/10.13005/ojc/290317
Abstract:
A new cyclen based compound (5a,6,7,8,9,9a,15a,16,17,18,19,19a-dodecahydrodinaphtho[2,3-b:2’,3’-h][1,4,7,10]- tetraazacyclododecine-5,10,15,20-tetraone) was successfully synthesized from the reaction of naphthoquinone with ethylenediamine in a phosphate buffer/acetonitrile solution under mild reaction conditions in excellent yield.
Keywords:Naphthoquinone;Ethylenediamine;Cyclen-based Compound;Phosphate buffer/acetonitrile solution;Medicine
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