ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Abstract

Synthesis of a New Cyclen-based Compound as a Potent Anti-tumor Medicine

Davood Habibi1* Hiva Nabavi2, Somayyeh Heydari2, Somayyeh Vakili2

DOI : http://dx.doi.org/10.13005/ojc/290317


Abstract:

A new cyclen based compound (5a,6,7,8,9,9a,15a,16,17,18,19,19a-dodecahydrodinaphtho[2,3-b:2’,3’-h][1,4,7,10]- tetraazacyclododecine-5,10,15,20-tetraone) was successfully synthesized from the reaction of naphthoquinone with ethylenediamine in a phosphate buffer/acetonitrile solution under mild reaction conditions in excellent yield.

Keywords:

Naphthoquinone;Ethylenediamine;Cyclen-based Compound;Phosphate buffer/acetonitrile solution;Medicine

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