ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Abstract

Zn[(L)-proline]2: A Novel and Recyclable Catalyst for the Synthesis of 2-Aryl-4(3H)-quinazolinones in Solvent-Free Conditions

Naser Montazeri¹*, Khalil Pourshamsian¹, Mahdi Fouladi² and Masoud Bayazi¹


Abstract:

An efficient, solvent-free and facile synthesis of 3-aryl quinazolinones from cyclocondensation of 2-aminobenzamides with aryl aldehydes catalyzed by Zn[(L)-proline]2 in the presence of CuCl2 is described. The salient features of the reaction include good yields , mild reaction conditions , low loading of catalyst , and operational simplicity. The catalyst is reusable and can be applied several times without considerable decrease in the yields and rates of the reactions.

Keywords:

2-Aryl quinazolinones; Zn[(L)-proline]2; Solvent-free Conditions; Recyclable Catalyst

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