Abstract

Neeraj Sharma* and Pawan Sharma

The synthesis of metal complexes of mixed ligand nitrosalicylaldehyde & b- diketones with transition metal ions such as Mn(II), Cu(II), Co(II) and Ni(II) .The complexes have been characterized by elemental analysis, molar conductance, TLC, IR. The molecular formula of mixed ligand complexes corresponds to [ML1L2(NO3)2 ] where M = [Mn(II), Cu(II), Co(II) and Ni(II) ], L1 = 2- Hydroxy-5- nitrobenzaldehyde & L2 = b- Diketones. All the mixed ligand complexes have been screened for their antimicrobial activity against fungi viz. A niger, A. flavous, P. triticena, F. species and bacteria viz. E. coli, B. subtilis, S. typhi, S. aureus. The results of antimicrobial activity show that mixed ligand complex of Cu (II) have more potency towards experimental fungi and bacteria. It also shows that mixed ligand complex of Cu (II) is more toxic against bacteria S. aureus.The complexes were found to be nonelectrolyte in nature on the basis of low value molar conductance.

Antimicrobial activities; mixed ligand complexes; transition metal ions

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