Abstract
A Facile Solvent free Microwave Induced Synthesis of Chlorine Containing Pyrazoline and Isoxazoline Derivatives and their Phytotic Impact on Some Flowering Plants And Antimicrobial Activity
Sonal D. Boob and P.R. Rajput
Abstract:
Eight New chlorine containing 4-Aroyl/Alkoyl-D2-pyrazolines and isoxazolines have been synthesized with 80-85% yield by a microwave promoted solvent-free condensation of 3-aroyl/alkoylflavanones 5a-d respectively with phenylhydrazine hydrochloride and hydroxylaminehydrochloride over potassium carbonate The work-up is simple and involves treatment with ice-cold water. A considerable increase in the reaction rate has been observed, with better yields.
Keywords:Pyrazolines; Isoxazolines solid-phase synthesis; condensation flavanones; microwaves effect
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