ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
     FacebookTwitterLinkedinMendeley

Abstract

Synthesis and Biological Studies of Some 2,3-Diphenylthiazolidin-4-ones and Condensed Pyrazolines

A. K.  Nag


Abstract:

2,3-Diphenylthiazolidin-4-one and its different benzylidenes have been used as the starting material in the present work. 4-Thiazolidinones are known to exhibit antitubercular, antibacterial, anticonvulsant, antifungal, antithyroid activities. These benzylidene derivatives possess unsaturated carbonyl group which are further allowed to react with hydrazine hydrate and its phenyl derivatives to form different pyrazoline rings after cyclisation. Pyrazolines are found to be antipyretic, and show good antimicrobial and antifungal properties.

Keywords:

diphenylthiazolidinones; bezylidenes; pyrazolines; biological activities; antifungal; antimicrobial

[ View HTML Full Text]

Back to TOC