Abstract

E. JAYACHANDRAN

Various substituted 3-{7-substituted-6-1,3 -benzothiazol-2-yl-1-({4-methylphenyl) sulfonyl]20thixo-2,3dihydroquinazolin –4 (1H)-one and 2-[(4Z)-4-benzylidine-2-phenyl-5-oxo-4,5- dihydro-1H-imidazole-1-yl]-N-(7-substituted-6-fluro-1,3-benzothiazole-2-yl) benzamide containing different functional groups have been synthesized by condensing Ethylchloroformate with substituted 2-aminobenzothiazoles in presence dry acetone and K2CO3. The identity of compounds were confirmed on the basis of their spectral (UV-Visible, IR, 1H NMR and MASS) data. Further, they have been screened for their antimicrobial, antiinflammatory, anticonvulsant and anthlmentic activities.

Fluorine; Benzothiazole; sulphonamide; imidazole; quinazolin

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