Abstract

Javad Azizian^1*, Abolghasem shameli², Saeed Balalaie³, Mohammad Mehdi Ghanbari⁴, Shahab Zomorodbakhsh^5, Mahdieh Entezari⁵, Saleh Bagheri² and Ghasem Fakhrpour²  

1,4-diazabicyclo[2.2.2]octane (DABCO) was used as a catalyst for one-pot, three-component condensation reactions consisting of aromatic aldehydes, malononitrile and thiobarbituric acid in aqueous ethanol at room temperature. This method has the advantages of a simple operation,mild reaction conditions, high yields, by using a less toxic and low cost chemical as a catalyst.

thiobarbuturbic acid; malononitrile; DABCO; Aldehyde; Catalyst

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