Abstract

M. Sugumaran* and D. Jothieswari

A simple, rapid and sensitive method has been developed for the quantitative estimation of valacyclovir hydrochloride in bulk and tablet. The wavelength 252 nm was selected for the concentration range 4-24μg/ml. The accuracy of the method was assessed by recovery studies and was found between 99.61-101.28%. The method was statistically validated for the linearly, precision, accuracy repetability. LOD, LOQ and ruggedness. The method was successfully applied for routine analysis of this drug in bulk and formulations.

Valacyclovir; UV-spectroscopy; validation and recovery

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