ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Abstract

Mild and Efficient Synthesis of B-Amino Alcohols by Bismuthtrichloride Catalysed Opening of Epoxides

A. Thirupathaiah1*, S. Ramanna2 and G. Venkateswar Rao2


Abstract:

Nucleophilic opening of epoxides with aniline derivatives in the presence of catalytic amount of bismuthtrichloride in acetonitrile at room temperature afforded the corresponding b-amino alcohols in excellent to very good yield.

Keywords:

Epoxide; bismuthtrichloride; nucleophilic opening; aromatic amine; b-aminoalcohols

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