ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Abstract

Synthesis and Characterization of Some New Imidazo [2,1-A] Pyrazolo [3,4-D] Thiazoles as Potentials Fungicide

Atma Ram Mishra*, Vivek Srivastava and Abu Shahma


Abstract:

The new cis-3,3a-imidazo[2,1-a]-pyrazolo[3,4-d] thiazoles (IIa-l) have been synthesized by refluxing a mixture of 2-(p-ethoxy arylidene-5,6-dehydro imidazo [2,1-a]-thiazolidene-3-one(IIa-f) with hydrazine hydrate or 2,4-di-nitro phenyl hydrazine and anhydrous sodiumacetate in glacial acetatic acid. All the synthesized compounds have been characterized by elemental analysis & spectral data and also screened for their fungicidal activity against two fungal species that is Alternaria solanai & Puccinia recondita. Screening data have been co-related with the structural feature of the tested compounds.

Keywords:

Alternaria solanai; Puccinia recondita; Agar plate technique; Thiazoles; imidazoles and spectral analysis

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