ISSN : 0970 - 020X, ONLINE ISSN : 2231-5039
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Abstract

Synthesis, characterization and antibacterial screening of some novel biphenyl-4-carboxylic acid (4-benzylidene- 5-oxo-2-subsituted phenyl-4,5-dihydro-imidazol-1-yl)-amide

Vijay Trivedi1* and Shailesh H. Shah2


Abstract:

Imidazolinone derivatives of 4a-l have been prepared by the condensation of biphenyl-4-carboxylic acid hydrazide 2 with 5-oxazolone derivatives, which were prepared by Erlenmeyer condensation of benzoyl glycine with different aldehydes in the presence of sodium acetate and acetic anhydride. The compounds 3a-l was further reacted with biphenyl-4-carboxylic acid hydrazide 2 to give 4a-l in basic condition. The constitution of the products has been supported by IR, 1H-NMR, 13C-NMR Mass spectra and Elemental analysis data.

Keywords:

Imidazolinone derivatives; synthesis; antibacterial screening

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