Abstract

Haniyeh Alavi1, Milad Taheri^* and Mehdi Daryani

Amino Acids are consider as main base units forming peptide & Protein’s composites. They‘re playing important role in defining and forming or making them (Amino Acids) artificially in chemical labs. In this research, converting Glycine Amino Acid (without Chiral Carbon) to desirable Amino acids through proper C- alkylation’s process in salty chemical environment with present of phase transfer catalyst. With the present of Glycine as well as  alkyl agent in Organic phase & base in water Phase and a Phase transfer catalyst forming Mono anion at phase as a mono alkylation Glycine  product controlled production. As mentioned the aim of this research is the chiral amino acids synthesis. Glycine Amino acid is Chosen as a base abundant material in nature. Then every artificial compositions purified. Following compositions has recrystallization with petroleum ether and formed the production through chromatogram of (TLC), then detecting by comparing their RF with other composition’s RF to prove & support the production’s purifications grade. And then for final result, in order to define clearly and completely, 1H-NMR and other methods such as IR and Mass spectrums measuring we have been used. Achieved results from composed productions shows, their formations and performance is depended on proper composition periods (speed). s ed om composed es has been used

Chiral; Synthesis; α-Amino Acid; mono alkylation Glycine

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